Health Canada > Explanatory note for the Covid-19 Interim Order

Do mRNA vaccines stay in the shoulder or travel throughout the bloodstream?

…Compare this to what happens in vaccination. The injection is intramuscular, not into the bloodstream. That’s why a muscle like the deltoid is preferred, because it’s a good target of thicker muscle tissue without any easily hit veins or arteries at the site of injection. The big surface vein in that region is the cephalic vein, and it’s down along where the deltoid and pectoral muscles meet, not high up in the shoulder. In earlier animal model studies of mRNA vaccines, such administration was clearly preferred over a straight i.v. injection; the effects were much stronger. So the muscle cells around the injection are hit by the vaccine (whether mRNA-containing lipid nanoparticles or adenovirus vectors) while a good portion of the remaining dose is in the intercellular fluid and thus drains through the lymphatic system, not the bloodstream. That’s what you want, since the lymph nodes are a major site of immune response. The draining lymph nodes for the deltoid are going to be the deltoid/pectoral ones where those two muscles meet, and the larger axillary lymph nodes down in the armpit on that side.

Now we get to a key difference: when a cell gets the effect of an mRNA nanoparticle or an adenovirus vector, it of course starts to express the Spike protein. But instead of that being assembled into more infectious viral particles, as would happen in a real coronavirus infection, this protein gets moved up to the surface of the cell, where it stays. That’s where it’s presented to the immune system, as an abnormal intruding protein on a cell surface. The Spike protein is not released to wander freely through the bloodstream by itself, because it has a transmembrane anchor region that (as the name implies) leaves it stuck. That’s how it sits in the virus itself, and it does the same in human cells. See the discussion in this paper on the development of the Moderna vaccine, and the same applies to all the mRNA and vector vaccines that produce the Spike. You certainly don’t have the real-infection situation of Spike-covered viruses washing along everywhere through the circulation. The Spike protein produced by vaccination is not released in a way that it gets to encounter the ACE2 proteins on the surface of other human cells at all: it’s sitting on the surface of muscle and lymphatic cells up in your shoulder, not wandering through your lungs causing trouble.

Some of the vaccine dose is going to make it into the bloodstream, of course.

Matt Taibbi: Moral Majority Media Strikes Again

When Rachel Maddow, Rolling Stone, and others jumped on a dubious report of ivermectin overdoses, it was just the latest in a string of moral mania mishaps

Researchers in The Netherlands have warned that Pfizer-BioNTech’s vaccine induces complex reprogramming of innate immune responses

Researchers in The Netherlands and Germany have warned that Pfizer-BioNTech’s coronavirus disease 2019 (COVID-19) vaccine induces complex reprogramming of innate immune responses that should be considered in the development and use of mRNA-based vaccines.

Covid Class Action Constitutional Challenge

The Canadian Society for the Advancement of Science in Public Policy (CSASPP) is a non-profit, non-partisan, secular, crowd funded, and volunteer driven organization that was created in response to popular community demand for a direct action initiative to counter BC’s COVID-19 related measures. We are collecting contact information for concerned healthcare workers affected by the mandated covid vaccination policy in BC who are interested in taking part in a class action lawsuit. This includes those who may have gotten the injection. More information will be sent out via email once available.

On child vaccines, the experts are suddenly reluctant to follow ‘the science’

Into the void between our scientific knowledge and our fear of mortality has rushed politics. It is a refusal to admit that “the science” is necessarily compromised by political and commercial considerations that has led to an increasingly polarized – and unreasonable – confrontation between what have become two sides of the Covid divide. Doubt and curiosity have been squeezed out by the bogus certainties of each faction.

[2018] Vaccines Are Pushing Pathogens to Evolve

The team found that, over the course of their lives, the unvaccinated birds shed far more of the least virulent strains into the environment, whereas the vaccinated birds shed far more of the most virulent strains. The findings suggest that the Marek’s vaccine encourages more dangerous viruses to proliferate. This increased virulence might then give the viruses the means to overcome birds’ vaccine-primed immune responses and sicken vaccinated flocks.

Virus czar calls to begin readying for eventual 4th vaccine dose

Israel’s national coronavirus czar on Saturday called for the country to begin making preparations to eventually administer fourth doses of the coronavirus vaccine. […] This is our life from now on, in waves,” he said.

WHO asks wealthy nations to hold off on Covid vaccine boosters at least through September

“The entire world is in the middle of this and as we’ve seen with the emergence of variant after variant, we cannot get out of it unless the whole world gets out of it together, and with the huge disparity in vaccination coverage, we’re simply not going to be able to achieve that,” Aylward said.

Harvard Epidemiologist Says the Case for COVID Vaccine Passports Was Just Demolished

…vaccinated individuals were 27 times more likely to get a symptomatic COVID infection than those with natural immunity from COVID.