Category Archives: Studies
Increases in COVID-19 are unrelated to levels of vaccination across 68 countries and 2947 counties in the United States – European Journal of Epidemiology
At the country-level, there appears to be no discernable relationship between percentage of population fully vaccinated and new COVID-19 cases in the last 7 days (Fig. 1). In fact, the trend line suggests a marginally positive association such that countries with higher percentage of population fully vaccinated have higher COVID-19 cases per 1 million people. Notably, Israel with over 60% of their population fully vaccinated had the highest COVID-19 cases per 1 million people in the last 7 days. The lack of a meaningful association between percentage population fully vaccinated and new COVID-19 cases is further exemplified, for instance, by comparison of Iceland and Portugal. Both countries have over 75% of their population fully vaccinated and have more COVID-19 cases per 1 million people than countries such as Vietnam and South Africa that have around 10% of their population fully vaccinated.
USF researchers find chlorine dioxide gas 99.91% effective against COVID-19 virus – College of Public Health News
After one hour, there was a 99.91 percent reduction in the virus versus a non-treated control. After two hours, there was a 99.997 percent reduction.
“This work demonstrates that chlorine dioxide gas can be an effective disinfectant [allowing for] little to no exposure and rapid degradation of residuals,” Harbison said. “Relatively short fumigation of enclosed spaces, such as patient rooms, classrooms and inside ambulances and emergency vehicles, would allow for fast sterilization with less manual labor required of the cleaning staff. What’s more,” Harbison added, “chlorine dioxide is a gas and has the advantage of reaching places liquid disinfectants cannot, providing better efficacy for eliminating the virus.”
COPH research team finds chlorine dioxide gas 99.91% effective against COVID-19 virus - College of Public Health News
COVID-19 has taught us a lot of things. And one of the more important lessons has been the need for thorough, fast and effective disinfecting measures. A team of researchers from the USF College of Public Health’s (COPH) Center for Environmental/ Occupational Risk Analysis an…
Rapid initiation of nasal saline irrigation to reduce morbidity and mortality in COVID+ outpatients
SARS-CoV-2+ participants initiating nasal irrigation were over 8 times less likely to be hospitalized than the national rate.
Rapid initiation of nasal saline irrigation to reduce morbidity and mortality in COVID+ outpatients: a randomized clinical trial compared to a national dataset
Importance SARS-CoV-2 enters the nasopharynx to replicate; mechanical debridement with nasal irrigation soon after diagnosis could reduce morbidity and mortality. Objective To determine whether initiating nasal irrigation after COVID-19 diagnosis reduces hospitalizations and death, and whether irri…
Study Reveals Declining COVID-19 Vaccine Efficacy Against Infection
Today’s report tracked the cohort through August 14—incorporating over four more months of data that include a time period in which the Delta variant swept the country—and found that overall, vaccine effectiveness dipped to 66 percent in the weeks when the variant accounted for at least 50 percent of SARS-CoV-2 viruses sequenced. What the study can’t answer is why effectiveness dipped in the weeks dominated by Delta.
[Preprint] Comparing SARS-CoV-2 natural immunity to vaccine-induced immunity: reinfections versus breakthrough infections
SARS-CoV-2-naïve vaccines had a 13.06-fold (95% CI, 8.08 to 21.11) increased risk for breakthrough infection with the Delta variant compared to those previously infected, when the first event (infection or vaccination) occurred during January and February of 2021.
Comparing SARS-CoV-2 natural immunity to vaccine-induced immunity: reinfections versus breakthrough infections
Background Reports of waning vaccine-induced immunity against COVID-19 have begun to surface. With that, the comparable long-term protection conferred by previous infection with SARS-CoV-2 remains unclear. Methods We conducted a retrospective observational study comparing three groups: (1)SARS-CoV-…
Ivermectin > Long Known Antiviral Qualities
…cell culture experiments show robust antiviral action towards HIV-1, dengue virus (DENV), Zika virus, West Nile virus, Venezuelan equine encephalitis virus, Chikungunya virus, Pseudorabies virus, adenovirus, and SARS-CoV-2
Ivermectin as a Broad-Spectrum Host-Directed Antiviral: The Real Deal?
The small molecule macrocyclic lactone ivermectin, approved by the US Food and Drug Administration for parasitic infections, has received renewed attention in the last eight years due to its apparent exciting potential as an antiviral. It was identified ...
Researchers in The Netherlands have warned that Pfizer-BioNTech’s vaccine induces complex reprogramming of innate immune responses
Researchers in The Netherlands and Germany have warned that Pfizer-BioNTech’s coronavirus disease 2019 (COVID-19) vaccine induces complex reprogramming of innate immune responses that should be considered in the development and use of mRNA-based vaccines.
Research suggests Pfizer-BioNTech COVID-19 vaccine reprograms innate immune responses
Researchers in The Netherlands have warned that Pfizer-BioNTech’s coronavirus disease 2019 (COVID-19) vaccine induces complex reprogramming of innate immune responses that should be considered in the development and use of mRNA-based vaccines.
Vitamin D Studies
A Spanish randomized controlled trial found a 96% reduction in the risk of requiring intensive care in patients receiving high-dose vitamin D (100,000 IU).
https://www.sciencedirect.com/science/article/pii/S0960076020302764
Another randomized trial in Spain with 930 hospitalized patients found a reduction in ICU treatment of 80% and in mortality of 60% in patients receiving high-dose vitamin D.
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3771318
A study in a French nursing home found an 89% decrease in mortality in residents who had received high-dose vitamin D either shortly before or during covid-19 disease.
https://www.sciencedirect.com/science/article/pii/S096007602030296X
A retrospective British study of approximately 1000 hospitalized covid patients found an 80% reduction in mortality with high-dose vitamin D.
https://www.mdpi.com/2072-6643/12/12/3799
A large Israeli study found a strong link between vitamin D deficiency and covid-19 severity.
https://www.medrxiv.org/content/10.1101/2020.09.04.20188268v1
Another Israeli study observed a significant decrease of the odds for hospitalization for COVID-19 patients treated with either vitamin D or magnesium citrate.
https://www.medrxiv.org/content/10.1101/2020.10.13.20211953v3.full-text
Ivermectin Studies
The mechanisms of action of Ivermectin against SARS-CoV-2: An evidence-based clinical review article | The Journal of Antibiotics:
https://www.nature.com/articles/s41429-021-00430-5
The broad spectrum host-directed agent ivermectin as an antiviral for SARS-CoV-2:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577703/
A review of the anti-viral effects of ivermectin | African Journal of Clinical and Experimental Microbiology:
https://www.ajol.info/index.php/ajcem/article/view/209853
Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen | The Journal of Antibiotics
https://www.nature.com/articles/s41429-020-0336-z
Quantitative proteomics reveals a broad‐spectrum antiviral property of ivermectin, benefiting for COVID‐19 treatment – Li – 2021 – Journal of Cellular Physiology – Wiley Online Library:
https://onlinelibrary.wiley.com/doi/10.1002/jcp.30055
Ivermectin Docks to the SARS-CoV-2 Spike Receptor-binding Domain Attached to ACE2:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652439/
And the rest of the other Ivermectin studies and meta-analysis: